Transgender Hormone Replacement Therapy

SottoPelle® Method providers have been helping transgender & gender diverse patients live as their true and authentic selves with bio-identical HRT pellet therapy since the mid 1990’s. This natural approach is more identical to the body’s own hormone delivery system, leading to more effective results, with fewer side-effects and risks than synthetic hormones

Hormone Replacement for Transgender & Gender Diverse Patients

SottoPelle® has helped thousands of transgender & gender diverse people during and after transition. Bio-identical hormone therapy naturally and safely provides the required hormones for transition, aligning the patient’s sexual characteristics with their gender identity.

Transgender & gender diverse people have often faced a long struggle to reconcile their inner identity with their outer body. Facing so many challenges and decisions, it is important to understand the pros and cons of various hormone replacement therapies (HRT). We have helped thousands of & gender diverse people across the United States who require HRT during and after transition. Bio-identical hormone therapy naturally and safely provides the required hormones for transition, aligning the patient’s sexual characteristics with their gender identity.

The SottoPelle® bioidentical hormone method is effective whether the goal of hormone treatment is feminization or masculinization. In other words, BHRT can be used for male-to-female or female-to-male transition. Because hormone therapy is a lifetime commitment for & gender diverse people, most patients desire a natural therapeutic solution, that is safe and effective for long-term use without dangerous side effects.

HRT for Transgender & Gender Diverse People

Transgender & gender diverse people have many choices when it comes to hormone replacement methods. The challenge is finding one that will make your transition easier, and also can maintain hormonal balance for a lifetime – safely, easily and without side-effects.

There are many choices when it comes to hormone replacement methods. The challenge is finding one that will make your transition easier, and also can maintain hormonal balance for a lifetime – safely, easily and without side-effects. There needs to be continuous and ongoing low dosage of hormone delivered as the body requires it. Release of testosterone and/or estradiol directly into the blood-stream, bypassing the gastrointestinal system and liver is preferred. Bioidentical hormone replacement pellets are consistently proven more effective than oral, injected, or topical methods with regard to sexual function, mood and cognitive function, metabolic function, bone density, urinary, prostate and vaginal problems, lipid profiles, breast health and hormone ratios. BHRT pellets are a solution that has long lasting results, with NO daily maintenance, and NO dangerous side-effects from long-term use.

Hormone Therapy for Transgender & Gender Diverse People

Bioidentical hormones are identical on a molecular level to the body’s own hormones, making them safer & more effective than synthetics. Time-released pellets are the only BHRT method that can release hormones 24/7, as the body needs them.

SottoPelle® uses the most reliable hormone delivery system available – long-lasting, time released pellet implants. Our proprietary personalized dosing system is based in science, not guesswork. This enables SottoPelle® physicians to precisely determine the proper low dosage of bioidenticals for transgender & gender diverse people. We use a time proven insertion method to assure a consistent steady delivery of testosterone and/or estradiol, 24/7.

SottoPelle® has been doing this a lot longer than most, with 30+ years of experience, we understand exactly what it takes to create a healthy state of balance and well-being for you. Remember, not all hormone or pellet therapies are alike or work well. It takes consistent hormonal balance to sustain a healthy body and support your health as you transition and thereafter.

Transgender & Gender Diverse Hormone Replacement Method

Why SottoPelle®?

Following the SottoPelle® Method, 100% natural HRT pellets are administered by physicians – for the safest and most effective results during and after your transition. Daily pills, painful shots, conspicuous patches, and messy creams and gels are not practical for a long-term solution. In addition to being a constant hassle, these antiquated hormone delivery methods do not promote natural quality in your true identity and lifestyle.

But bioidentical hormone therapy pellets only need to be inserted once every four to six months in a quick 10 minute procedure. In addition to being safer and more natural, bioidentical HRT pellets are much simpler, more effective and offer greater consistency of delivery.

Every treatment is customized for the individual transgender or gender diverse patient’s unique hormone balancing needs – and we monitor any potential health risks closely – working in tandem with you and your other participating physicians.

 –  Testimonials  –

What People Say About Us

SottoPelle® Patient Testimonial

Patient Testimonial Jim McMahon

Hear directly from patients
sharing their wellness journey
and results.

Patient Testimonial Liz

Learn how personalized hormone care
supports energy, mood, and overall
well-being.

Patient Testimonial Brad Soden

Discover what makes the SottoPelle®
the trusted leader in bio identical
hormone replacement therapy.

Why the SottoPelle® Hormone Method?

Once inserted, a steady, low dose of natural hormone flows directly into the blood stream whenever the body needs it. This gives the body the ability to control the release of the hormones just as it did when the ovaries and testicles were working normally.

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Feeling great has
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You’re an original and unique. Our pellet therapy is tailored to each patient’s precise and individual needs. We use safe state of the art technology to provide you with personalized patient treatment and care. SottoPelle® helps you reconnect with the best you can be at any age.